Cavrois et al. challenge the popular "Trojan horse" model of HIV-1 trans-infection, saying that their recent studies, among others, show that the vast majority of virions transmitted in trans originate from the plasma membrane rather than from intracellular vesicles.
Kilpatrick et al. examine factors that determine the spread of two strains of West Nile virus (WNV) in the Americas. They suggest that both viral evolution and temperature influence the distribution and intensity of transmission of WNV, and provide a model for predicting the impact of temperature and global warming on virus transmission.
Lorenz et al. hypothesize that Xanthomonas campestris pv. Vesicatoria, the cause of bacterial spot disease in pepper and tomato plants, first undergoes pilus formation before injecting itself into the host cell cytosol.
Moriarty et al. show spirochete dissemination in vivo by engineering a fluorescent strain of Borrelia burgdorferi and using conventional and spinning disk confocal microscopy to directly visualize the bacteria in real time and 3D in living mice.
PLoS Pathogens is an open-access journal that publishes important new ideas on bacteria, fungi, parasites, prions, and viruses that contribute to our understanding of the biology of pathogens and pathogen-host interactions.
E-mail Alerts
RSS (What is RSS?)
Join PLoSRead the PLoS Blog 
and contribute your views on scientific research and open-access publishing.
All site content, except where otherwise noted, is licensed under a Creative Commons Attribution License.
